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Ceritinib is an anaplastic lymphoma kinase (ALK)-positive inhibitor primarily used for the treatment of metastatic NSCLC. Previously, it was only indicated for patients who had developed resistant to crizotinib, another ALK-positive inhibitor, but has since had its usage expanded to serve as a primary option for metastatic NSCLC.

Pemetrexed injection is used in combination with other chemotherapy medications as a first treatment for a certain type of non-small cell lung cancer (NSCLC) that has spread to nearby tissues or to other parts of the body.

. Pemetrexed injection is also used alone to treat NSCLC as ongoing treatment in people who have already received certain chemotherapy medications and whose cancer has not worsened and in people who could not be treated successfully with other chemotherapy medications. Pemetrexed injection is also in combination with another chemotherapy medication as a first treatment for malignant pleural mesothelioma (a type of cancer that affects the inside lining of the chest cavity) in people who cannot be treated with surgery.

. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain substance in the body that may help cancer cells multiply.

. Pemetrexed injection comes as a solution (liquid) and as a powder to be mixed with liquid to be injected into a vein over 10 minutes. Pemetrexed injection is administered by a doctor or nurse in a medical office or infusion center. It is usually given once every 21 days.Request
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Vinorelbine is used alone and in combination with other medications to treat non-small cell lung cancer (NSCLC) that has spread to nearby tissues or to other parts of the body. Vinorelbine is in a class of medications called vinca alkaloids. It works by slowing or stopping the growth of cancer cells in your body.

Geftinib 250 mg is used to treat adults with non-small cell lung cancer (locally advanced or distance spread [metastasis]).
Geftinib 250 mg blocks a protein called ‘epidermal growth factor receptor’ (EGFR) which is involved in the growth and spread of cancer cells.

Cyramza (Ramucirumab 500 mg) Injection is an anticancer medication. It is used in the treatment of non-small cell lung cancer, stomach cancer and cancer of colon and rectum. It is given as IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. High blood pressure is a very common side effect of this medicine. Hence, your doctor will monitor your blood pressure regularly while taking this medicine. You should remain hydrated as it may also cause diarrhea and headache as its side effects. It is known to reduce the red blood cells in your blood. Hence, regular blood tests are required to monitor your blood cells during treatment with this medicine. USES OF CYRAMZA INJECTION Non-small cell lung cancer Stomach cancer Cancer of colon and rectum BENEFITS OF CYRAMZA INJECTION In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Cyramza 500mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. In Stomach cancer Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Cyramza 500mg Injection helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. In Cancer of colon and rectum Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Cyramza 500mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. Show Less SIDE EFFECTS OF CYRAMZA INJECTION Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Cyramza High blood pressure Diarrhea Headache Decreased sodium level in blood Anemia (low number of red blood cells) HOW TO USE CYRAMZA INJECTION Your doctor or nurse will give you this medicine. Kindly do not self administer. HOW CYRAMZA INJECTION WORKS Cyramza 500mg Injection is an anticancer medication. It works by blocking the ‘VEGF receptor 2’ thereby cutting off the blood supply to the cancer cells. This slows the growth of cancer cells and eventually kills them. SAFETY ADVICE warnings Alcohol CAUTION Caution is advised when consuming alcohol with Cyramza 500mg Injection. Please consult your doctor.

Fluorouracil belongs to the group of medicines known as antimetabolites. It is used to treat cancer of the colon, rectum, breast, stomach, and pancreas. It may also be used to treat other kinds of cancer, as determined by your doctor.

. Fluorouracil interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by fluorouracil, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
. Before you begin treatment with fluorouracil, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
. Fluorouracil is to be administered only by or under the immediate supervision of your doctor.

Abiraterone Acetate Tablets IP 250mg, sold under the brand name Zytiga among others, is an antiandrogen medication which is used in the treatment of prostate cancer. It is specifically indicated for use in conjunction with castration and prednisone for the treatment of metastatic castration-resistant prostate cancer (mCRPC) and in the treatment of metastatic high-risk castration-sensitive prostate cancer (mCSPC). It is taken by mouth once per day on an empty stomach.

Bevacizumab Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing. Avastin 100mg Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Abevmy 100mg Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. USES OF ABEVMY INJECTION Cancer of colon and rectum Non-small cell lung cancer Kidney cancer Brain tumor Ovarian cancer Cervical cancer BENEFITS OF ABEVMY INJECTION In Cancer of colon and rectum Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Abevmy 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Abevmy 100mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. In Kidney cancer Abevmy 100mg Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. In Brain tumor Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Abevmy 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Consult your doctor if you have any doubts.

Krabeva (Bevacizumab 100mg,400mg) Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing. Krabeva 100mg Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Krabeva 100mg Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. USES OF KRABEVA INJECTION Cancer of colon and rectum Non-small cell lung cancer Kidney cancer Brain tumor Ovarian cancer Cervical cancer BENEFITS OF KRABEVA INJECTION In Cancer of colon and rectum Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Krabeva 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Krabeva 100mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. In Kidney cancer Krabeva 100mg Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. In Brain tumor Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Krabeva 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Consult your doctor if you have any doubts. In Ovarian cancerRequest
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Lapatinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop or slow the spread of cancer cells.

Docetaxel injection is used alone or in combination with other medications to treat certain types of breast, lung, prostate, stomach, and head and neck cancers. Docetaxel injection is in a class of medications called taxanes. It works by stopping the growth and spread of cancer cells.

. Docetaxel injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.

. Docetaxel injection is also sometimes used to treat ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed). Talk to your doctor about the risks of using this drug for your condition.

Bortezomib for Injection is used to treat certain types of cancer such as multiple myeloma (a cancer of the cells of the immune system in the bone marrow) and mantle cell lymphoma (a cancer of the cells of the immune system affecting the lymph nodes).
It works by stopping or slowing down the growth and spread of cancer cells in the body.Request
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Fludacel 50mg Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in blood. This slows the growth of cancer cells and eventually kills them.

Docetaxel 120mg Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

. Docetaxel 120mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Docetax 120mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Docetaxel 120mg Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

. Docetaxel 120mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Docetax 120mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Paclieva Paclitax 300mg Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.

. Paclitax 300mg Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.

. Paclitax 300mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Paclitax 300mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.Request
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Quercetin has antioxidant and anti-inflammatory effects that might help reduce swelling, kill cancer cells, control blood sugar, and help prevent heart disease. Quercetin is most commonly used for conditions of the heart and blood vessels.

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

Azacitidine (trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer.

INDICATIONS AND USAGE.
 
1.Eliquis is a factor Xa inhibitor anticoagulant indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation . 

.DOSAGE AND ADMINISTRATION.

1] The recommended dose is 5 mg orally twice daily.(2.1)
2] In patients with at least 2 of the following characteristics: age 80 years, body weight 60 kg, or serum creatinine 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily. (2.2)

DOSAGE FORMS AND STRENGTHS.

- Tablets: 2.5 mg and 5 mg (3)

.WARNINGS AND PRECAUTIONS.

1.ELIQUIS can cause serious, potentially fatal bleeding. Promptly evaluate signs and symptoms of blood loss. (5.2).
2. Prosthetic heart valves: ELIQUIS use not recommended.

 .ADVERSE REACTIONS.

1] Most common adverse reactions (>1%) are related to bleeding.
2] (6.1) To report SUSPECTED ADVERSE REACTIONS, contact Bristol-Myers Squibb at 1-800-721-5072 or FDA at 1-800-FDA-1088

--------------------------------DRUG INTERACTIONS----------------------------- 

1. Strong dual inhibitors of CYP3A4 and P-gp increase blood levels of apixaban: Reduce ELIQUIS dose to 2.5 mg or avoid concomitant use. (2.2, 7.1, 12.3)
2.Simultaneous use of strong inducers of CYP3A4 and P-gp reduces blood levels of apixaban: Avoid concomitant use. (7.2, 12.3).Request
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Cizumab (Bevacizumab 100mg,400mg) is used in combination with other anti-cancer drugs in the treatment of various types of cancers like lung cancer, ovarian cancer , brain cancer and colon or rectal cancer .

Side effects of Bevacizumab includes include: 

• Headache Seizure High blood pressure Sluggishness Confusion Blindness . Apart from these it may also lead to kidney problem , infusion site reaction, dry skin, back pain etc.

NA CONTRAINDICATIONS OF VERSAVO 400MG INJECTION:

• Bevacizumab is contraindicated in following conditions, consult your doctor if you experience any of them; Decrease of Neutrophils in the Blood from Cancer Chemotherapy High blood pressure Heart attack OR angina Chronic heart failure Transient ischemic attack Bleeding Gastrointestinal fistula Nephrotic syndrome Recent operation Pregnancy Breastfeeding mother

MECHANISM OF ACTION OF VERSAVO 400MG INJECTION:

• Bevacizumab is a anti-angiogenic drug. It demonstrates its anti-cancer action by blocking vascular endothelial growth factor (VEGF) protein. Thereby stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.

SPECIAL PRECAUTIONS FOR VERSAVO 400MG INJECTION:

• Bevacizumab may cause infusion-related reactions, which can be life-threatening and require immediate medical attention.

CONTENT DISCLAIMER:

•  intended to provide diagnosis, treatment or medical advice. Products, Services, Information and other content provided on this site are for informational purposes only. SastiMedicine does not recommend self management of health issues, information on this is site is not comprehensive and does not cover all diseases, ailments, physical conditions or their treatment. Contact your healthcare professional for any diagnosis or treatment options.

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Lenvatinib 4mg ,10mg  is a prescription medicine that is used to treat certain kinds of cancer. Lenvatinib  is used by itself to treat differentiated thyroid cancer (DTC), a type of thyroid cancer that can no longer be treated with radioactive iodine and is progressingLenvatinib  is used along with another medicine called everolimus to treat advanced renal cell carcinoma (RCC), a type of kidney cancer, after one course of treatment with another anti-cancer medicineLenvatinib  is used by itself as the first treatment for a type of liver cancer called hepatocellular carcinoma (HCC) when it cannot be removed by surgeryIt is not known if Lenvatinib  is safe and effective in children.

Nintedanib, sold under the brand names BDR and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

Mebex Mebendazole is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies.

This medicine is available only with your doctor's prescription.

Tamoxifen is used to treat breast cancer that has spread to other parts of the body in men and women. It is used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.

Tamoxifen is used to treat breast cancer that has spread to other parts of the body in men and women. It is used to treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.

Letrozole belongs to a group of medicines called aromatase inhibitors. Aromatase inhibitor medicines are used to treat certain types of breast cancer, where the cancer cells need oestrogen (a hormone) in order to grow. Additional Information: Delivery Time: 7 to 10 days Packaging Details: box type

Bevarest (Bevacizumab 100mg,400mg) Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing. Bevarest 100mg Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Bevarest 100mg Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. USES OF BEVAREST INJECTION Cancer of colon and rectum Non-small cell lung cancer Kidney cancer Brain tumor Ovarian cancer Cervical cancer BENEFITS OF BEVAREST INJECTION In Cancer of colon and rectum Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Bevarest 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Bevarest 100mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated. In Kidney cancer Bevarest 100mg Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover. In Brain tumor Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Bevarest 100mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Consult your doctor if you have any doubts.

Imatinib Capsules IP tablet is used in the treatment of blood cancers, bone marrow disorders, skin cancer and certain tumours of the stomach and the digestive tract.
Imatinib Mesylate belongs to a class of medications called kinase inhibitors. It works by preventing abnormal protein activity which signals cancer cells to multiply and spread across the body, thus inhibiting the growth of these abnormal cells.

Paclitaxel is a chemotherapy medication that destroys fast-dividing cancer cells. It treats several types of cancers including ovarian cancer, breast cancer and lung cancer. A healthcare provider will give you this medication by infusion into your vein in a hospital or clinic setting.

. Paclitaxel  is a chemotherapy drug. It targets fast dividing cells, like cancer cells, and causes these cells to die. This medicine is used to treat ovarian cancer, breast cancer, lung cancer, Kaposi's sarcoma, and other cancers.

Ibrunat (Ibrutinib 140mg)contains the Drug/Molecule called “Ibrutinib”. Ibrunat is a small molecule drug that is used to bind permanently to a protein called “Bruton’s tyrosine kinase (BTK)” which is important in B cells.

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

How Ibrunat Ibrutinib 140 mg Capsule Works

Ibrutinib which is the active ingredient in Ibrunat 140 mg capsules, works in a manner that it blocks the activity of a specific protein called “Bruton’s tyrosine kinase”, or BTK.

Bruton’s tyrosine kinase is a protein that is found in your B cells and it sends “signals” to the other parts of the body that help B cells to survive and multiply.

But these generic ibrunat capsules block BTK & help in killing and reducing the number of cancerous B-cells. Therefore, this stops or slows the progression of cancer.

How to Take Ibrunat Capsule
It is prescribed to take Ibrunat 140 mg once in a day at about the same time every day. The dosage and duration of treatment depends on the type of blood cancer, the age of the patient, and on how severe the condition of the patient.

Moreover, it also depends on “how the patient’s body reacts to the first dose.” The Natco Ibrunat Capsules should be taken orally with a glass of water. Please remember to not to open, crush, or chew the capsules.

Side Effects of Ibrunat Capsules
Ibrunat can cause side effects like:

• Bleeding
• Leukostasis
• Infections
• Decrease the blood cell counts
• Heart problems or Liver problems.

There are chances of occurring the new cancers in people taking Ibrunat, including skin cancer & other cancers.

The most common side effects may include:

• Pneumonia
• Upper respiratory tract infection
• Diarrhea
• Feeling very tired
• nausea
• headache
• swollen hands
• ankles or feet
• being short of breath
• dizziness
• fainting
• constipation and infected nose.

Interactions with other drugs

• Some antiplatelet drugs like “Clopidogrel”, “NSAIDs like Ibuprofen / Naproxen”, “Blood thinners like Warfarin / Dabigatran” can cause bleeding / bruising with Ibrunat capsules.
• The drug called aspirin can increase the risk of bleeding if it is used with Ibrunat Ibrutinib.
• And lastly, the azole antifungals drugs such as “Itraconazole”, “Ketoconazole” can affect the removal of Ibrunat from body.

Overdose 

• You shouldn’t take more than prescribed dose.
• The patients who have received doses higher than the recommended quantity should be carefully monitored. And most importantly, don’t ever take extra dose for the missed dose.

Precaution 
The patients taking ibrunat shouldn’t take it with grapefruit or Seville oranges. Which includes eating these fruits, drinking the juice, or taking the supplements that mat contain these fruits. It is prescribed not to take these fruits because these can increase the amount of Ibrunat in blood.

Pemetrexed injection is used in combination with other chemotherapy medications as a first treatment for a certain type of non-small cell lung cancer (NSCLC) that has spread to nearby tissues or to other parts of the body.

. Pemetrexed injection is also used alone to treat NSCLC as ongoing treatment in people who have already received certain chemotherapy medications and whose cancer has not worsened and in people who could not be treated successfully with other chemotherapy medications. Pemetrexed injection is also in combination with another chemotherapy medication as a first treatment for malignant pleural mesothelioma (a type of cancer that affects the inside lining of the chest cavity) in people who cannot be treated with surgery.

. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain substance in the body that may help cancer cells multiply.

. Pemetrexed injection comes as a solution (liquid) and as a powder to be mixed with liquid to be injected into a vein over 10 minutes. Pemetrexed injection is administered by a doctor or nurse in a medical office or infusion center. It is usually given once every 21 days.

 Fluorouracil belongs to the group of medicines known as antimetabolites. It is used to treat cancer of the colon, rectum, breast, stomach, and pancreas. It may also be used to treat other kinds of cancer, as determined by your doctor.

. Fluorouracil interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by fluorouracil, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
. Before you begin treatment with fluorouracil, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
. Fluorouracil is to be administered only by or under the immediate supervision of your doctor.

Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles.

. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body.

. This medicine is to be given only by or under the direct supervision of a doctor.

OLAPARIB is a prescription medicine used to treat adults who have:
advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer with a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene. OLAPARIB is used alone as maintenance treatment after the cancer has responded to your first treatment with platinum-based chemotherapy. Your healthcare provider will perform a test to make sure that OLAPARIB is right for youovarian cancer, fallopian tube cancer, or primary peritoneal cancer, as maintenance treatment, when the cancer has come back. OLAPARIB is used after the cancer has responded to treatment with platinum-based chemotherapyadvanced ovarian cancer with a certain type of abnormal inherited BRCA gene, and have received treatment with 3 or more prior types of chemotherapy medicines. Your healthcare provider will perform a test to make sure that OLAPARIB is right for youa certain type of abnormal inherited BRCA gene, human epidermal growth factor receptor 2 (HER2)-negative breast cancer that has spread to other parts of the body (metastatic). You should have received chemotherapy medicines, either before or after your cancer has spread. If you have hormone receptor (HR)-positive disease, you should have been treated with hormonal therapy. Your healthcare provider will perform a test to make sure that OLAPARIB is right for you.IMPORTANT SAFETY INFORMATION OLAPARIB may cause serious side effects, including:Bone marrow problems called Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML). Some people who have ovarian cancer or breast cancer and who have received previous treatment with chemotherapy, radiotherapy, or certain other medicines for their cancer have developed MDS or AML during treatment with OLAPARIB. MDS or AML may lead to death. If you develop MDS or AML, your healthcare provider will stop treatment with OLAPARIB.
Symptoms of low blood cell counts are common during treatment with OLAPARIB, but can be a sign of serious bone marrow problems, including MDS or AML. Symptoms may include weakness, weight loss, fever, frequent infections, blood in urine or stool, shortness of breath, feeling very tired, bruising or bleeding more easily.
Your healthcare provider will do blood tests to check your blood cell counts:before treatment with OLAPARIBevery month during treatment with OLAPARIBweekly if you have low blood cell counts that last a long time. Your healthcare provider may stop treatment with OLAPARIB until your blood cell counts improveLung problems (pneumonitis). Tell your healthcare provider if you have any new or worsening symptoms of lung problems, including shortness of breath, fever, cough, or wheezing. Your healthcare provider may do a chest x-ray if you have any of these symptoms. Your healthcare provider may temporarily or completely stop treatment if you develop pneumonitis. Pneumonitis may lead to death.
Before taking OLAPARIB, tell your healthcare provider about all of your medical conditions, including if you:have lung or breathing problemshave kidney problemsare pregnant, become pregnant, or plan to become pregnant. OLAPARIB can harm your unborn baby and may cause loss of pregnancy (miscarriage)If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with OLAPARIBFemales who are able to become pregnant should use effective birth control (contraception) during treatment with OLAPARIB and for 6 months after the last dose of OLAPARIB. Talk to your healthcare provider about birth control methods that may be right for you. Tell your healthcare provider right away if you become pregnant or think you might be pregnant following treatment with OLAPARIBMales with female partners who are pregnant or able to become pregnant should use effective birth control (contraception) during treatment with OLAPARIB and for 3 months after the last dose of OLAPARIB

Lenvatinib (trade name Lenvima) is an anti-cancer drug for the treatment of certain kinds of thyroid cancer, and potentially for other cancers as well. It was developed by Eisai Co. and acts as a multiple kinase inhibitor against the VEGFR1, VEGFR2 and VEGFR3 kinases. LENVIMA (lenvatinib) is a prescription medicine that is used to treat certain kinds of cancer.Request
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MOZOBIL (plerixafor) injection is indicated in combination with filgrastim to mobilize hematopoietic stem cells (HSCs) to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) or multiple myeloma

Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles.

. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body.

. This medicine is to be given only by or under the direct supervision of a doctor.

Docetaxel injection is used alone or in combination with other medications to treat certain types of breast, lung, prostate, stomach, and head and neck cancers. Docetaxel injection is in a class of medications called taxanes. It works by stopping the growth and spread of cancer cells.

. Docetaxel injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.

. Docetaxel injection is also sometimes used to treat ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed). Talk to your doctor about the risks of using this drug for your condition.